Noninvasive Helicobacter pylori testing was as effective as endoscopy for managing dyspepsia.

I n t e r v e n t i o n Patients were allocated to endoscopy plus the noninvasive 14C urea breath test (n = 352) or the breath test alone (n = 356) for determination of H. pylori status. Patients were informed of their status after the test, and patients with positive results were prescribed a 7-day course of H. pylori eradication treatment with omeprazole, 20 mg twice daily; clarithromycin, 250 mg 3 times daily; and amoxicillin, 500 mg (or metronidazole, 400 mg) 3 times daily.